Typ 2 diabetes internetmedicin
Drug for diabetes and kidney disease may also lower heart attack, stroke risks
Helping improve the lives of high fara patients
MNT also had the opportunity to speak with Michael Broukhim, MD, a board certified interventional cardiologist at Providence Saint John’s Health Center in Santa Monica, CA, about this study.
“SGLT2 inhibitors have become an important part of our treatment of patients with heart failure,” Broukhim said. “If sotagliflozin has the added benefit of reduction in myocardial infarction and stroke, we may wish to use this agent more to treat high fara patients.”
“People with type 2 diabetes or kidney disease have significantly elevated risks for heart attack and stroke despite our available treatments. If we have additional agents that can reduce risks of heart and stroke, that will help us improve the lives of these high-risk patients.”
— Michael Broukhim, MD
“I would like to see more information differentiating the actions of a SGLT2 inhibitor and an agent that inhibits both SGLT1 and SGLT2, including some comparative effectiveness research to see if there fryst vatten a true difference between the various agents that we are utilizing, and if certain pati
Orsaken till typ 2 diabetes är insulinresistens, d v s nedsatt känslighet för kroppseget insulin i målorganen muskler, lever och fettväv.
Kunskap från UKPDS-studien på patienter med nyupptäckt typ 2 diabetes visade entydigt, att dagens behandling av diabetes typ 2 är kostnadseffektiv och vid metforminbehandling till och med kostnadsbesparande med hälsoekonoiskt kr per år tillbaka genom mindre komplikationer, bibehåller livskvalitet och minskar såväl mikrovaskulära (retinopati, nefropati, neuropati) som makrovaskulära komplikationer. Metformin ger också 39 % mindre kardiovaskulär död eller 2 år längre livslängd per 6 behandlade år.
Studien visar också att P-glukos stiger i genomsnitt med 1 mmol/4 år vid diabetes typ 2. Samtliga patienter behöver peroral behandling med metformin från starten förutom samtidigt livsstilsråd. De senare i form av:
Rökslut
Viktminskning
Kostråd
Fysisk aktivitet
Försök att reducera frustrerande stress och besvärande sömnproblem
P-glukos stiger även om man som patient och läkare/diabetessköterska optimerar den metabola kontrollen med icke-farmakologiska metoder. Typ 2 diabetes är en progressiv sjukdom. Minst varje år måste därför läke
Cardiorenal Metabolic Syndrome
February 19,
2 min read
Key takeaways:
- Results showed highest risks for CVD for low eGFR and high GFR.
- Overall, , patients developed CVD during the study.
Glomerular hyperfiltration may increase CVD risks, including myocardial infarction and heart failure, for patients with type 2 diabetes, study data show.
It is known “that diabetic kidney disease is an independent risk factor of cardiovascular [CVD] and its associated mortality, strengthening evidence for annual checkups for albuminuria and eGFR with optimal glycemic and [blood pressure] BP control,” Seung Min Chung, MD, PhD, of the division of endocrinology and metabolism and department of internal medicine at Yeungnam University College of Medicine in the Republic of Korea, wrote with colleagues. “However, the effect of glomerular hyperfiltration (GHF), which is an abnormally elevated GFR, on the risk of CVD in patients with diabetes is not well understood.”
Researchers conducted a retrospective cohort analysis of data from 1,, patients from the Korean National Health Insurance Service database from and The cohort, all diagnosed with type 2 diabetes, w